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Stopping empirical antifungal therapy early based on a predefined set of criteria in children with high risk febrile neutropenia is safe: a randomized feasibility trial

Not Applicable
Conditions
Health Condition 1: B49- Unspecified mycosis
Registration Number
CTRI/2021/02/031563
Lead Sponsor
All India Institute of Medical Sciences New Delhi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Having high risk febrile neutropenia and being started on empirical anti-fungals

Exclusion Criteria

1.Treatment with therapeutic antifungal in the preceding 14 days

2.Residence >1 hour of reach from the hospital

3.Non-availability of reliable and compliant caretaker

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Breakthrough fungal infectionTimepoint: 28 days from randomisation
Secondary Outcome Measures
NameTimeMethod
All cause mortalityTimepoint: 28 days from randomisation;Antifungal free daysTimepoint: 28 days from randomisation;Rehospitalization rateTimepoint: 28 days from randomisation
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