Prediction Of Pre eclampsia at Early Gestatio

• Conditions: P02; O14.9; Pre-eclampsia, unspecified; Fetus and newborn affected by complications of placenta, cord and membranes

• Registration Number: DRKS00014630
• Lead Sponsor: Institute for Prenatal Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-06-01
• Study Completion: 2020-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 444

Inclusion Criteria

normal singleton pregnancy of women age 18 or older between 11+0 and 13+6 weeks of gestation

Exclusion Criteria

- fetuses with morphological malformations or aneuploidies
- necessity of drug treatment of hypertension, or rheumatic diseases
- taking ASS at any time during the pregnancy

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Delivery (control group)<br>oder<br>(pre-eclampsia group)<br>- protein excretion 2+ (60mg/dl)<br>or<br>- systolic blood pressure with two consecutive measurements at intervals of 2-7 days of 140 mm Hg<br>or<br>- diastolic blood pressure with two consecutive measurements at intervals of 2-7 days of 90 mm Hg<br>or<br>- clinical signs of HELLP syndrome

Secondary Outcome Measures

Name	Time	Method
Secondary outcome is to validate published data about the distribution of PAPP-A and PlGF