Salivary Alkaline Phosphatase as a Biomarker for Dental Caries in A Group of Egyptian Children With Different Growth Rates: A Descriptive Cross-Sectional Study

Not yet recruiting

• Conditions: Dental Caries in Children

• Registration Number: NCT05607251
• Lead Sponsor: Cairo University

Brief Summary

Aim of the study:

1. Assess the correlation between salivary alkaline phosphatase levels and dental caries.

2. Assess the effect of growth of children on the levels of salivary alkaline phosphatase enzyme.

3. Assess the effect of growth of children on caries experience and severity.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-11
• Study First Submitted: 2022-11-01
• Study First Submitted QC: 2022-11-01
• Last Update Submitted: 2022-11-01
• Study First Posted: 2022-11-07
• Last Update Posted: 2022-11-07
• Study Start: 2023-01
• Primary Completion: 2023-03
• Study Completion: 2023-04

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

• Children aged 6 to 8 years old.
• Children with and without previous dental visits.

Exclusion Criteria

• Children with any systemic or mental illness.
• Children whose parents refuse to sign the informed consent.
• Children who will not cooperate on participation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Salivary Alkaline Phosphatase levels in children with and without dental caries	2 months	Measured by spectrophotometry (unit: U/L)

Secondary Outcome Measures

Name	Time	Method
Caries index	2 months	Measured by DMFT and deft (unit: scores)
Caries severity	2 months	Measured by ICDAS (unit: scores)