toxic effect of creatine supplementatio
Not Applicable
- Conditions
- Drug or medicament, unspecified.Drug or medicament, unspecified
- Registration Number
- IRCT201305124663N15
- Lead Sponsor
- niversity of Tabriz
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 27
Inclusion Criteria
Inclusion:male; 18-26 years old; healthy; wrestling athletes;BMI<12; at least 3 years of professional wrestling experience; without any creatine consumption( during 3 months prior to the stud) Exclusion: Diseases; Injuries; Uncontrolled intake of creatine supplements during the period
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method rinary formaldehyde. Timepoint: 24 hour before and after the Cr loading phase. Method of measurement: Gas chromatography–mass spectrometry (GC-MS).;Ceartine kinase (CK). Timepoint: 24 hour before and after supplementation protocol. Method of measurement: photometric methods with commercial kits (Bionik kit).;Lactate Dehydrogenase(LDH). Timepoint: 24 hour before and after supplementation protocol. Method of measurement: photometric methods with commercial kits (Bionik kit).;Alanine aminotransferase (ALT). Timepoint: 24 hour before and after supplementation protocol. Method of measurement: photometric methods with commercial kits (Bionik kit).;Aspartate aminotransferase (AST). Timepoint: 24 hour before and after supplementation protocol. Method of measurement: photometric methods with commercial kits (Bionik kit).
- Secondary Outcome Measures
Name Time Method Blood Pressure. Timepoint: 30 minutes before and after firs and last trainig session. Method of measurement: Aneroid blood pressure measurement.