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Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers

Completed
Conditions
Healthy Volunteers
Registration Number
NCT00152724
Lead Sponsor
University Hospital, Angers
Brief Summary

Microvascular dysfunctions are critical events in several diseases including diabetes. This study will develop a methodology for microvascular investigation in human skin. The purpose of the study is to investigate the physiological response of the cutaneous microcirculation to physical, thermal, mechanical or chemical stimulations.

Detailed Description

This study has investigated various aspects of the physiology of the microcirculation in the past years and is still recruiting under parallel protocols of physiological investigations of the neurovascular control of the cutaneous microcirculation.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
85
Inclusion Criteria
  • Healthy volunteers with no clinical signs of, or risk factors for, vascular disease
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Exclusion Criteria
  • Smokers, Pregnancy, Allergy,
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Amplitude of the vasomotor response to stimuli1 hour
Secondary Outcome Measures
NameTimeMethod
Kinetics of the vasomotor response to stimuli1 hour

Trial Locations

Locations (1)

Laboratoire de Physiologie et Explorations Vasculaires - CHU Angers

🇫🇷

Angers, France

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