Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers

Completed

• Conditions: Healthy Volunteers

• Registration Number: NCT00152724
• Lead Sponsor: University Hospital, Angers

Brief Summary

Microvascular dysfunctions are critical events in several diseases including diabetes. This study will develop a methodology for microvascular investigation in human skin. The purpose of the study is to investigate the physiological response of the cutaneous microcirculation to physical, thermal, mechanical or chemical stimulations.

Detailed Description

This study has investigated various aspects of the physiology of the microcirculation in the past years and is still recruiting under parallel protocols of physiological investigations of the neurovascular control of the cutaneous microcirculation.

Study Timeline

• Study Start: 1996-01
• Study First Submitted: 2005-09-08
• Study First Submitted QC: 2005-09-08
• Study First Posted: 2005-09-09
• Status Verified: 2007-03
• Primary Completion: 2008-11
• Study Completion: 2008-11
• Last Update Submitted: 2017-10-30
• Last Update Posted: 2017-11-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 85

Inclusion Criteria

• Healthy volunteers with no clinical signs of, or risk factors for, vascular disease

Exclusion Criteria

• Smokers, Pregnancy, Allergy,

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Amplitude of the vasomotor response to stimuli	1 hour

Secondary Outcome Measures

Name	Time	Method
Kinetics of the vasomotor response to stimuli	1 hour

Trial Locations

Locations (1)

Laboratoire de Physiologie et Explorations Vasculaires - CHU Angers; 🇫🇷 Angers, France