?Exir research project of desferoxamin with brand name of Deferoxir
Not Applicable
- Conditions
- thalassemia major.Cooley anaemia Severe beta thalassaemia Thalassaemia: intermedia major
- Registration Number
- IRCT2015012620818N1
- Lead Sponsor
- exir pharmacutical company
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Patients with major thalassemia under regular blood injection therapy;. age over 5; undergoing treatment with one of deferoxamine pharmaceutical products; Norma renal function; serum cratinine undr 0. 7; in children under the age of 12 less than 1.0; in teenagers less than 1.1; and in over 16 years old pateinets (female less than 1.2; male less than 1.2); Trans aminase enzymes level less than 2 times of normal range; BUN<22mg/dl.
Exclusion Criteria
Any experience of allergic reaction to desferoxamine, positive HCV Ab / HBS Ag.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ferritin. Timepoint: every 2 month from begining of study. Method of measurement: blood test.;SGOT. Timepoint: every 2 month from begining of study. Method of measurement: blood test.;SGPT. Timepoint: every 2 month from begining of study. Method of measurement: blood test.;Cr. Timepoint: every 2 month from begining of study. Method of measurement: blood test.;WBC. Timepoint: every 2 weeks. Method of measurement: blood test.;Hgb. Timepoint: every 2 weeks from begining of study. Method of measurement: blood test.;Platlet. Timepoint: every 2 weeks from begining of study. Method of measurement: blood test.
- Secondary Outcome Measures
Name Time Method Optometry. Timepoint: before study,6 months after begining of study,12 months after beginig of study. Method of measurement: optometry.;T2*MRI. Timepoint: before study,6 months after begining of study,12 months after beginig of study. Method of measurement: blood test.;Audiology. Timepoint: before study,6 months after begining of study,12 months after beginig of study. Method of measurement: Audiology.;Sonography. Timepoint: before study,6 months after begining of study,12 months after beginig of study. Method of measurement: Sonography.