The role of free fatty acids in the glucose-lowering effects of thiazolidinediones
Completed
- Conditions
- Diabetes Mellitus type II (DM type II)Nutritional, Metabolic, EndocrineNon-insulin dependent diabetes
- Registration Number
- ISRCTN47118569
- Lead Sponsor
- Academic Medical Centre (Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 13
Inclusion Criteria
1. Obese patients with Diabetes Mellitus type II (DM II)
2. Body mass index (BMI) >25 kg/m2
3. Treatment for DM II with oral medication only
4. Moderately regulated DM II
Exclusion Criteria
1. Use of insulin
2. Use of fibrates
3. Plasma creatinine >150 umol/l
4. Transaminases >2 x upper limit of reference value
5. Impaired cardiac function or angina pectoris
6. Familial lipid metabolism disorder
7. Premenopausal women
8. Epilepsy
9. Proliferative retinopathy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method