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临床试验/NL-OMON40700
NL-OMON40700已完成不适用

Regulation of lipid metabolism by fructose versus glucose in obese humans with and without hepatic steatosis and its relation to insulin sensitivity - Carbohydrate regulation of lipids

Academisch Medisch Centrum0 个研究点目标入组 36 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
36

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • -eligible and scheduled for bariatric surgery (gastric bypass)
  • -18-65 years of age
  • -ability to provide informed consent
  • -stable weight 3 months prior to inclusion
  • -willingness to stop lipid lowering medication 4 weeks prior to start

排除标准

  • -primary lipid disorder
  • -childhood onset obesity (i.e. <12 years of age)
  • -use of exogenous insulin, GLP1 agonists or DDP4 inhibitors
  • -all medica! and psychiatric conditions except for obesity-related diseases
  • -coagulation disorders
  • -uncontrolled hypertension (blood pressure >150/95 mmHg)
  • -renal insufficiency (plasma creatinin >150 umol/l)
  • -excessive alcohol intake (>14 units/week)
  • -pregnancy, breastfeeding
  • -contraindication to MR scanning (e.g. pacemaker, metallic foreign body, claustrophobia)

研究者

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