NL-OMON40700已完成不适用
Regulation of lipid metabolism by fructose versus glucose in obese humans with and without hepatic steatosis and its relation to insulin sensitivity - Carbohydrate regulation of lipids
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99(—)
入选标准
- •-eligible and scheduled for bariatric surgery (gastric bypass)
- •-18-65 years of age
- •-ability to provide informed consent
- •-stable weight 3 months prior to inclusion
- •-willingness to stop lipid lowering medication 4 weeks prior to start
排除标准
- •-primary lipid disorder
- •-childhood onset obesity (i.e. <12 years of age)
- •-use of exogenous insulin, GLP1 agonists or DDP4 inhibitors
- •-all medica! and psychiatric conditions except for obesity-related diseases
- •-coagulation disorders
- •-uncontrolled hypertension (blood pressure >150/95 mmHg)
- •-renal insufficiency (plasma creatinin >150 umol/l)
- •-excessive alcohol intake (>14 units/week)
- •-pregnancy, breastfeeding
- •-contraindication to MR scanning (e.g. pacemaker, metallic foreign body, claustrophobia)
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