跳至主要内容
临床试验/NCT00829335
NCT00829335已完成不适用

Anatomical Segmental and Subsegmental Resection of the Liver for Hepatocellular Carcinoma: a New Approach by Means of Ultrasound-Guided Vessel Compression

University of Milan1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2007年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
1
主要终点
Technical feasibility

研究概览

简要总结

Anatomical resection is the gold standard approach for liver resection in patients with HCC. A new method for that by means of IOUS-guided finger compression has been devised.

详细描述

We herein describe a novel technique for the demarcation of the resection area by means of IOUS-guided finger compression to systematically accomplish anatomical segmental and subsegmental resections.

Using the IOUS, the tumor and the level targeted for compression are identified. Than, under the IOUS guidance, the surgeon compresses bilaterally the liver at the targeted position resulting in the compression of the portal pedicle feeding the tumor previously identified. This maneuver is constantly monitored in real-time just using the same microconvex probe, and it is maintained until the surface of the targeted liver area begins to discolor, at that time the first assistant marks the discolored area with the electrocautery, and the compression is released. Once the area is demarcated, liver dissection is started under intermittent Pringle's maneuver.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Patients suitable for surgical approach carries of HCC
  • Serum bilirubin level lower than 1.5 mg/dl

排除标准

  • Presence of ascites
  • Serum bilirubin level equal or higher than 1.6 mg/dl
  • Conditions (size, vascular relation, or infiltration) demanding resection larger than a segmental area
  • Tumor thrombus in portal or hepatic veins

结局指标

主要结局

Technical feasibility

次要结局

  • Morbidity and mortality(30 and 90 days)

研究者

申办方类型
Other

研究点 (1)

Loading locations...

相似试验