NCT01489150CompletedNot Applicable
Use of EtCO2 and Prolonged Expiratory Maneuvers as a PaCO2 Predictor in Cases of Acute Hypercapnic Respiratory Failure
University of Lausanne Hospitals1 site in 1 country11 target enrollmentStarted: December 2011Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 11
- Locations
- 1
- Primary Endpoint
- Comparison between EtCO2,PaCO2 and PaCO2 variation under NIV during both spontaneous expiration and prolonged expiration
Study Overview
Brief Summary
In patients treated by Non invasive ventilation (NIV) due to acute hypercapnic respiratory failure, the interest of using the End-tidal Co2 measurement device "Capnostream" to evaluate PaCo2 and PaCo2 variations over time will be evaluated. Measurements will be done under normal expiration and under prolonged active and passive expiration maneuvers.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •ICU patient equipped with arterial line
- •NIV requirement
- •Hypercapnia: PaCO2 > 45mmhg
Exclusion Criteria
- •Severe hemodynamic instability
- •Severe psychiatric disorders
- •nasal lesions
- •denied consent
Outcomes
Primary Outcomes
Comparison between EtCO2,PaCO2 and PaCO2 variation under NIV during both spontaneous expiration and prolonged expiration
Time Frame: Sixty minutes
Comparison between EtCO2,PaCO2 and PaCO2 variation under NIV during both spontaneous expiration and prolonged expiration
Secondary Outcomes
No secondary outcomes reported
Investigators
Prof. Philippe Jolliet
Principal investigator
University of Lausanne Hospitals
Study Sites (1)
Loading locations...
Similar Trials
Completed
Not Applicable
Use of TpCO2 (Transcutaneous CO2 Measurement) as PaCO2 Predictor During NIV in Case of Acute Hypercapnic Respiratory FailureHypercapnic Respiratory FailureNCT01857635University of Lausanne Hospitals20
Recruiting
Not Applicable
NIV for Hypercapnic Respiratory Failure: AVAPS vs S/T BIPAPHypercapnic Respiratory FailureNCT06047405Northwell Health100
Unknown
Not Applicable
Non-invasive Ventilation in Patients With Interstitial Lung Disease - a Feasibility StudyNoninvasive VentilationLung Diseases, InterstitialNCT02377739Schön Klinik Berchtesgadener Land30
Completed
Not Applicable
Extracorporeal CO2 Removal in Hypercapnic PatientsPulmonary Disease, Chronic ObstructiveNCT02564406University of Roma La Sapienza35
Completed
Phase 4
Helmet Ventilation in Acute Hypercapnic Respiratory FailureHypercapnic Respiratory FailureChronic Obstructive Pulmonary DiseaseNCT01645358IRCCS Azienda Ospedaliero-Universitaria di Bologna80