Use of TpCO2 (Transcutaneous CO2 Measurement) as PaCO2 Predictor During NIV in Case of Acute Hypercapnic Respiratory Failure

Completed

• Conditions: Hypercapnic Respiratory Failure

• Registration Number: NCT01857635
• Lead Sponsor: University of Lausanne Hospitals

Brief Summary

In patients suffering from hypercapnic respiratory failure and treated by non invasive ventilation (NIV), the interest of using transcutaneous CO2 measurement to evaluate PaCO2 and PaCO2 variation over time is unknown and will be evaluated in this study. Measurements will be done during one-hour NIV treatments.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-02
• Study First Submitted: 2013-05-15
• Study First Submitted QC: 2013-05-15
• Study First Posted: 2013-05-20
• Primary Completion: 2015-03
• Study Completion: 2015-03
• Status Verified: 2015-06
• Last Update Submitted: 2015-06-07
• Last Update Posted: 2015-06-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• ICU patient equipped with an arterial line
• NIV treatment prescribed by the clinician in charge
• Hypercapnia defined by PaCO2> 42mmHg

Exclusion Criteria

• Severe hemodynamic instability
• Severe psychiatric disorders
• Denied consent
• Age < 18 years

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison between TpCO2 (transcutaneous non invasive CO2 partial pressure measurement) and PaCO2 (obtained by blood gas analysis) values during NIV treatment.	sixty minutes

Trial Locations

Locations (1)

Intensive care and burn unit, University hospital of Lausanne; 🇨🇭 Lausanne, Switzerland