Use of EtCO2 as a PaCO2 Predictor Under Non Invasive Ventilation (NIV) in Cases of Acute Hypercapnic Respiratory Failure

Completed

• Conditions: Hypercapnic Respiratory Failure

• Registration Number: NCT01489150
• Lead Sponsor: University of Lausanne Hospitals

Brief Summary

In patients treated by Non invasive ventilation (NIV) due to acute hypercapnic respiratory failure, the interest of using the End-tidal Co2 measurement device "Capnostream" to evaluate PaCo2 and PaCo2 variations over time will be evaluated. Measurements will be done under normal expiration and under prolonged active and passive expiration maneuvers.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-12
• Study First Submitted: 2011-12-02
• Study First Submitted QC: 2011-12-07
• Study First Posted: 2011-12-09
• Primary Completion: 2012-04
• Study Completion: 2012-12
• Status Verified: 2013-05
• Last Update Submitted: 2013-05-15
• Last Update Posted: 2013-05-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 11

Inclusion Criteria

• ICU patient equipped with arterial line
• NIV requirement
• Hypercapnia: PaCO2 > 45mmhg

Exclusion Criteria

• Severe hemodynamic instability
• Severe psychiatric disorders
• nasal lesions
• denied consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison between EtCO2,PaCO2 and PaCO2 variation under NIV during both spontaneous expiration and prolonged expiration	Sixty minutes	Comparison between EtCO2,PaCO2 and PaCO2 variation under NIV during both spontaneous expiration and prolonged expiration

Trial Locations

Locations (1)

Intensive care and burn unit, University Hospital of Lausanne; 🇨🇭 Lausanne, Switzerland