A study on how using a blood product helps in faster healing after removing lower wisdom teeth

Not yet recruiting

Conditions: healthy human volunteers

Registration Number: CTRI/2025/06/089697

Lead Sponsor: Dr Chaitya Adalja

Brief Summary: Surgical extraction of third molar teeth is one of the most frequently performed procedures in oral surgery practice. Surgical extraction of third molars often results in pain, swelling, and trismus. While platelet concentrates like PRP and PRF have shown benefits in healing, limited research exists on concentrated growth factor (CGF), especially for partially erupted third molars. Concentrated growth factor (CGF), a third-generation platelet concentrate, has many advantages compared with first- and second-generation platelet concentrates, i.e., platelet-rich plasma (PRP) and platelet-rich fibrin (PRF). CGF is a new biomaterial discovered after platelet-rich plasma (PRP) and platelet rich fibrin (PRF), which contains a variety of high concentration growth factors and fibrin. As a concentrate from autologous blood, CGF can avoid the risk of immune rejection and can be safer and more economical than other fillers. This study aims to evaluate CGF’s effectiveness in reducing postoperative pain, swelling, and enhancing wound healing in 3rd molar surgeries.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 14

Inclusion Criteria

1 Patients having partially erupted mandibular 3rd molar 2 Patients american society of anaesthesiologist classification will be I or II.

Exclusion Criteria

1 Patients not willing to participate in study 2 Patients with uncontrolled comorbidity and medically compromised 3 Patients diagnosed with coagulopathy 4 Patients with comorbid periodontitis gingivitis or oral infectious disease 5 Patients using hormone therapy in the last 6 month.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
This study will help us to conclude effectiveness of using concentrated growth factor in 3rd molar surgery	This study will help us to conclude effectiveness of using concentrated growth factor in 3rd molar surgery at 1 week

Secondary Outcome Measures

Name	Time	Method

Trial Locations

Locations (1): Km shah dental college and hospital sumandeep vidyapeeth vadodara gujrat
🇮🇳
Vadodara, GUJARAT, India
Km shah dental college and hospital sumandeep vidyapeeth vadodara gujrat
🇮🇳Vadodara, GUJARAT, India
Dr chaitya adalja
Principal investigator
9687216320
adaljachaitya@gmail.com