The effect of Ginger powder consumption on some genes expression that are mediators of immunity and inflammation in adult with Rheumatoid Arthritis
Not Applicable
- Conditions
- adult active Rheumatoid arthritis.Rheumatoid arthritis, unspecified
- Registration Number
- IRCT201403109472N6
- Lead Sponsor
- Vice-chancellor for Research, Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
person with RA diseases as ACR criteria, having RA from 2 years ago; age between 18-69 years; not being pregnant or lactated; not smoking and drink alcohol; haven’t eaten multivitamin or antioxidants supplements from 3 month ago; don't eat lowering blood pressure; don't eat anti pregnancy drugs, exclusion criteria: Changes in diet or physical activity every day; taking less than 80% of supplements given to patients at baseline(the compliance lower than %80); consumption of contraceptives, multivitamins and antioxidant supplements; renal , hepatic , thyroid, parathyroid diseases, cancer, heart diseases
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method FkB Jene expression amount. Timepoint: Before and after study. Method of measurement: PCR.;PPAR? Jene expression amount. Timepoint: Before and after study. Method of measurement: PCR.;Foxp3 Jene expression amount. Timepoint: Before and after study. Method of measurement: PCR.;GATA3 Jene expression amount. Timepoint: Before and after study. Method of measurement: PCR.;T-bet Jene expression amount. Timepoint: Before and after study. Method of measurement: PCR.;ROR? Jene expression amount. Timepoint: Before and after the study. Method of measurement: PCR.
- Secondary Outcome Measures
Name Time Method BMI. Timepoint: Before and after study. Method of measurement: Formula.