Allergy Testing of Soldiers Prepared for International Mission

Not Applicable

Completed

• Conditions: Adult Military Personnel
• Interventions: Device: Skin Prick Automated Test

• Registration Number: NCT05807958
• Lead Sponsor: Queen Astrid Military Hospital

Brief Summary

The goal of this prospective mono centric study is to identify relevant commercially available allergen extracts for allergy testing in soldiers prepared for international mission.

Participants will receive a skin prick test with the skin prick automated test device including 22 allergens and 2 controls on both forearms.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-03-14
• Study First Submitted: 2023-03-14
• Study First Submitted QC: 2023-03-28
• Study First Posted: 2023-04-11
• Primary Completion: 2024-03-08
• Status Verified: 2025-02
• Study Completion: 2025-02-07
• Last Update Submitted: 2025-02-26
• Last Update Posted: 2025-02-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

• Adult military personnel (18-65y) will be included. Soldiers with and without previous exposure to allergens in the regions of interest will be included. Soldiers who are performing desk tasks and not selected for international missions will serve as controls.

Exclusion Criteria

• Skin pathology like chronic or exuberant urticaria, dermographism, chronic dermatitis that needs daily treatment
• Use of antihistaminic medication < 7 days before the start of the study
• Use of tricyclic antidepressants (antihistamine activity) < 7 days before the start of the study
• Use of topical corticoids on the forearm < 7 days before the start of the study
• Use of Omalizumab < 6 months before the start of the study
• Pregnancy: there is a remote possibility of inducing a systemic allergic reaction that could induce uterine contractions or necessitate the use of epinephrine (thought to cause constriction of the umbilical artery).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Skin Prick Automated Test	Skin Prick Automated Test	-

Primary Outcome Measures

Name	Time	Method
Allergens with positive skin reaction	baseline	Positive skin reactions of top ranked allergens required to identify 95% of sensitised individuals

Secondary Outcome Measures

Name	Time	Method
Work Performance & Activity Impairment	baseline	Total score of Work Performance \& Activity Impairment questionnaire, 0-100%, higher score means worse outcome
Self-reported allergic diseases	baseline	Percentage of soldiers with self-reported allergic diseases derived from questionnaire

Trial Locations

Locations (1)

Military Hospital Queen Astrid; 🇧🇪 Brussels, Belgium