Blood Pressure Responses to Different Exercise Modes in Coronary Artery Disease

Not Applicable

Completed

• Conditions: Coronary Artery Disease
• Interventions: Other: exercise

• Registration Number: NCT03847012
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

The purposes of this study were to compare blood pressure responses of the same target heart rate on different exercise modes in patients with coronary artery diseases (CAD) and to compare the effects of blood pressure responses after exercise training.

The investigators will recruit 30 subjects with CAD who are referred to phase II cardiopulmonary rehabilitation exercise training. The subjects performed the treadmill or stationary bicycle exercise randomly.

Detailed Description

Considering cardiopulmonary rehabilitation intensity is often setting by heart rate clinically, and only few study focused on exercise responses patients with CAD, the purposes of this study were to compare blood pressure responses of the same target heart rate on different exercise modes in patients with CAD and to compare the effects of blood pressure responses after exercise training.

This is a crossover trial study. The investigators will recruit 30 subjects with CAD who are referred to phase II cardiopulmonary rehabilitation exercise training. After at least 3 times of familiar with the cardiopulmonary rehabilitation training machine, the subjects performed the treadmill or stationary bicycle and exercise to personalized target heart rate for 10 minutes, take a rest until the heart rate recover to the resting heart rate, and then repeated the exercise in another exercise mode. The test order will be random. After at least 12 times of cardiopulmonary rehabilitation training, the test will be performed again.

Study Timeline

• Study First Submitted: 2019-02-10
• Study First Submitted QC: 2019-02-17
• Study First Posted: 2019-02-20
• Study Start: 2019-03-11
• Primary Completion: 2020-09-30
• Study Completion: 2020-09-30
• Status Verified: 2021-04
• Last Update Submitted: 2021-04-07
• Last Update Posted: 2021-04-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• patients with coronary artery diseases who are referred to phase II cardiopulmonary rehabilitation exercise training.

Read More

Exclusion Criteria

• patients with non-coronary artery diseases
• atrial fibrillation
• neurological or musculoskeletal problems

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
patients with coronary artery diseases	exercise	The investigators will recruit 30 subjects with CAD who are referred to phase II cardiopulmonary rehabilitation exercise training. After at least 3 times of familiar with the cardiopulmonary rehabilitation training machine, the subjects performed the treadmill or stationary bicycle and exercise to personalized target heart rate for 10 minutes, take a rest until the heart rate recover to the resting heart rate, and then repeated the exercise in another exercise mode.

Primary Outcome Measures

Name	Time	Method
heart rate	Change from baseline heart rate at 6 weeks	heart rate
blood pressure	Change from baseline blood pressure at 6 weeks	blood pressure

Secondary Outcome Measures

Name	Time	Method
perceived exertion scale	baseline and 6 weeks	how effort the participant feel. Range from 1to 10. Higher values represent harder.
heart rate variability	baseline and 6 weeks	heart rate variability

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei city, Taiwan