NCT07233941招募中不适用
Neuropsychological Profile Characterization in Patients With Migraine: Cognitive Functioning and Psychological Variables
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2025年9月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Cognitive functioning
研究概览
简要总结
The overall objective is to define the neuropsychological profile of patients with migraine and evaluate its association with: psychological outcome measures (anxiety-depressive symptoms, pain catastrophizing, excessive worry, and coping strategies); the clinical profile of migraine; the prodromal, ictal, or interictal phase of the migraine attack; pharmacological therapy; and detoxification treatment in patients with migraine associated with medication overuse headache.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Written informed consent.
- •Patients aged between 18 and 65 years.
- •Diagnosis of migraine according to the International Classification of Headache Disorders (ICHD-3) criteria.
- •Patients with a history of migraine for at least one year, to ensure the stability of the condition.
- •Stability of ongoing treatment for at least 3 months at baseline.
- •Understanding of the Italian language.
排除标准
- •Severe medical or psychiatric conditions (depression, schizophrenia, psychosis) documented by specific previous diagnoses.
- •A history of alcohol or drug abuse.
- •Primary sensory deficits.
结局指标
主要结局
Cognitive functioning
时间窗: 2 years
Neuropsychological test scores in migraine patients and proportion of participants with cognitive performance significantly different from age- and education-adjusted normative data.
次要结局
- Cognitive functions and psychological, clinical aspects(2 years)
- Cognitive functions and different pharmacological treatments(2 years)
- Cognitive functions and medication overuse headache(2 years)
- Cognitive functions in the different phases of migraine(2 years)
研究者
研究点 (1)
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