Management of Migraine through Ayurveda

Phase 2/3

Not yet recruiting

Conditions: Migraine, unspecified. Ayurveda Condition: ARDHAVABEDAKAH,

Registration Number: CTRI/2025/03/083175

Lead Sponsor: Institute for Ayurved Studies and Research

Brief Summary: Headache is the most common problem experienced by the individuals. Around 40% of

individuals worldwide are suffering from migraine. According to IHS (Indian Headache

Society),migraine constitutes 16% of the primary headache and affects about 10-20% of

general population (about 15% male and 6% female are the sufferers of the migraine). About

80% of patients have migraine without aura and 15-20% have migraine with aura.

It is more common in women than in men (3:1) and family history is present in more than 60%

of cases. Changing hormonal level also play a great role.

Hence, to find out such unique phenomenon of Ayurveda and to solve the problem of sufferers

of Migraine, Ardhavabhedaka (Migraine with and without aura) has been selected for the

present study. This study gives importance to break the samprapti of the disease.

In Ayurveda, the Acharyas have recognized the importance of medicines, especially of the

herbal medicines. Single drug treatment was the beginning point in the therapeutic regimen.

Total effects of all the ingredients in the formula rather than the action of individual drugs that

plays a vital role in therapeutics. There is no permanent treatment of migraine in modern

therapy. Treatment protocol is not fixed as no unique etiology, pathogenesis and diagnosis

criteria is known. Hence there is a need to develop safe and permanent treatment for Migraine.

Acharya Sushruta has shown Tridosha as the causative factor of Ardhavabhedaka, Acharya

Vagbhata and Charaka described Vata and Vata-Kapha. Pathyadi Kwath is mentioned in

Bhavaprakash for headache (Shiroroga). The decoction has ingredients having Ushana Virya and Vatashamak properties, which may be useful in management of Ardhavbhedaka.

In Ayurveda Nasya therapy has been considered as one of most promising

treatment for all the Urdhawajatrugata Vikaras. Nasya Karma involves administration of

herbal oil/drug/liquid into nostril which remove the blockages of the nasal pathways, relief

mental stress. These effects of Nasya gives significants relief in disease associated with nose

and head region such as Ardhavbhedaka (Migraine). Hence these drugs have been selected to

evaluate their efficacy in Ardhavbhedaka w.s.r. to Migraine.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

Age- 18-60 years 2.
Patients with sign and symptoms of Ardhavabhedaka (Migraine with or without aura) will be selected irrespective of Sex, Religion and Profession.
Patients those are fit for Nasya Karma according to Ayurveda text.
4.Patient willing to participate and able to provide signed informed consent.

Exclusion Criteria

1. Patient of age less than 18 years and more than 60 years. 2. The patient having any systemic illness, like.
Diabetes mellitus, Hypertension, Tuberculosis, Hypotension & fever etc. 3. Patients suffering from head injury, and other type of headaches except migraine. 4. Patients Contraindicated for Nasya Karma. 5. Pregnant and lactating mothers. 6. Secondary headache caused by sinusitis, meningitis, brain tumour, encephalitis, cervical spondylitis etc. 7. Patients with alcohol, opioids other drug addiction and using any other systemic drugs which may alter the result of study.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Significant improvement in intensity, frequency, duration of headache.	65 days
2.Reduction in scoring pattern of sign and symptoms of Ardhavabhedaka(Migraine)	65 days
along with nausea, vomiting, photophobia, phonophobia and aura.	65 days

Secondary Outcome Measures

Name	Time	Method
1. Improvement in mental & physical well being of patient.	2.Improvement in quality of life of patients.

Trial Locations

Locations (1): Institute for Ayurved Studies and Research Hospital
🇮🇳
Kurukshetra, HARYANA, India
Institute for Ayurved Studies and Research Hospital
🇮🇳Kurukshetra, HARYANA, India
Dr Vaishali
Principal investigator
8901120843
vaishaliyadav874@gmail.com