Cell-free DNA as a new, minimally invasive and sensitive biomarker for early detection of allograft rejection after heart transplantatio

• Conditions: cardiac surgery; heart disease; 10019280

• Registration Number: NL-OMON45738
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Adult (*18 years) heart transplant patients

Exclusion Criteria

No written informed consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Sensitivity: percentage of patients positive for rejection according to the<br /><br>golden standard EMB that are also positive according to the ddPCR technique. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable.</p><br>