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Clinical Trials/NCT05580263
NCT05580263
Completed
Not Applicable

The Effect of Different Order of Concurrent Training Consisting Aerobic and Resistance Exercise on Improving Visceral Adipose Tissue and Insulin Resistance for Community Residents With Obesity.

National Tainan Junior College of Nursing1 site in 1 country92 target enrollmentOctober 31, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Fat Burn
Sponsor
National Tainan Junior College of Nursing
Enrollment
92
Locations
1
Primary Endpoint
visceral adipose tissue
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Purposes: The purpose of one-year project is to compare the effect of different intrasession exercise order of AE and RE during concurrent training on reducing VAT and improving insulin resistance for inactive middle-age community residents with obesity.

Methods: Purposive sampling will be used to enroll community residents aged 40-64 years with inactive habit and body fat percentage ≧ 25% for male and ≧ 30% for female in southern Taiwan. Eligible participants will be stratified by sex and age (40-55years and 56-64 years) then block randomly divided into training group of AE preceding RE, RE preceding AE or a control group. The exercise training program will under supervision lasting 16 weeks with 3 times per week. The concurrent training prescription consist of AE 30 minutes and RE 15 minutes per session. A 5-minute interval between two exercise modalities. All participants will be evaluated outcomes for two time points including baseline (T0) and after 16-week intervention (T1). The primary outcomes are VAT and insulin resistance. A two-way ANOVA with repeated measures will be performed to compare changes of outcome variables over the intervention period.

Relevance to clinical practice: The results of this project can assist health professionals to know how to properly prescribe concurrent training of AE and RE to achieve the greatest effects on VATreduction and insulin resistance improvement for middle-age residents with obesity.

Detailed Description

Background: Visceral adipose tissue (VAT) accumulation is highly linking with cardiovascular diseases and insulin resistance. A combination of aerobic exercise (AE) and resistance exercise (RE) was an effective strategy to improve VAT and insulin resistance; however, no current evidence displayed whether the different orders of concurrent training (AE preceding RE or RE preceding AE) influence the effects on VAT reduction and insulin resistance improvement. Purposes: The purpose of one-year project is to compare the effect of different intrasession exercise order of AE and RE during concurrent training on reducing VAT and improving insulin resistance for inactive middle-age community residents with obesity. Methods: Purposive sampling will be used to enroll community residents aged 40-64 years with inactive habit and body fat percentage ≧ 25% for male and ≧ 30% for female in Tainan. Eligible participants will be stratified by sex and age (40-55years and 56-64 years) then block randomly divided into training group of AE preceding RE, RE preceding AE or a control group. The exercise training program will under supervision lasting 16 weeks with 3 times per week. The concurrent training prescription consist of AE 30 minutes and RE 15 minutes per session. A 5-minute interval between two exercise modalities. The control group will follow their primary lifestyle without exercise intervention. All participants will be evaluated outcomes for two time points including baseline (T0) and after 16-week intervention (T1). The primary outcomes are VAT and insulin resistance. VAT is measured by body composition analyzer and insulin resistance is calculate from fasting glucose and insulin level in blood samples. A two-way ANOVA with repeated measures will be performed to compare changes of outcome variables over the intervention period. Relevance to clinical practice: The results of this project can assist health professionals to know how to properly prescribe concurrent training of AE and RE to achieve the greatest effects on VATreduction and insulin resistance improvement for middle-age residents with obesity.

Registry
clinicaltrials.gov
Start Date
October 31, 2022
End Date
June 30, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Yu-Hsuan Chang

Assistant professor

National Tainan Junior College of Nursing

Eligibility Criteria

Inclusion Criteria

  • 40 to 64 years old.
  • body fat percentage ≧ 25% for male and ≧ 30% for female.
  • with inactive habit (≤ 3 days of physical activity per week and ≤ 30 min per session).
  • can communicate in Mandarin or Taiwanese.

Exclusion Criteria

  • with recent unstable conditions in which had potential risk on exercise including stroke, cardiovascular and respiratory diseases, handicap, pregnancy.
  • with any contraindications to body composition analyzer measurement including body embed pacemakers and artificial metal joints, amputated hands or feet.
  • cannot corporate with either examination or intervention.
  • use psychotropic or appetite-regulating medicine.
  • under oral hopoglycemic agent or insulin treatment.

Outcomes

Primary Outcomes

visceral adipose tissue

Time Frame: 16-week after intervention

Participants will measure visceral adipose tissue measure after 16-week intervention by body composition analyzer.

Insulin

Time Frame: 16-week after intervention

Participants will collect insulin after 16-week intervention by blood samples

Fasting glucose

Time Frame: 16-week after intervention

Participants will collect fasting glucose after 16-week intervention by blood samples

Secondary Outcomes

  • hip circumference(16-week after intervention)
  • weight(16-week after intervention)
  • body fat percentage(16-week after intervention)
  • waist circumference(16-week after intervention)

Study Sites (1)

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