Troponin I and T and Adverse Outcomes in Patients With and Without Diabetes Mellitus After Coronary Intervention

Completed

• Conditions: Coronary Artery Disease; Diabetes Mellitus
• Interventions: Other: Percutaneous coronary intervention

• Registration Number: NCT03627455
• Lead Sponsor: Wilhelminenspital Vienna

Brief Summary

Elevated levels of troponin are associated with future MACE. Data on the prognostic value of high sensitive troponin T (hs-TnT) as compared to high sensitive troponin I (hs-TnI) in diabetic and non-diabetic patients are sparse.

We aimed to assess the risk for MACE according to gender and diabetes status and to compare the prognostic value of hs-TnT and hs-TnI with regards to clinical outcomes in diabetic and non-diabetic patients undergoing percutaneous coronary intervention (PCI).

Detailed Description

Not available

Study Timeline

• Study Start: 2003-01-01
• Primary Completion: 2017-12-31
• Study Completion: 2017-12-31
• Status Verified: 2018-08
• Study First Submitted: 2018-08-08
• Study First Submitted QC: 2018-08-10
• Last Update Submitted: 2018-08-11
• Study First Posted: 2018-08-13
• Last Update Posted: 2018-08-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 818

Inclusion Criteria

• Percutaneous coronary intervention

Exclusion Criteria

• unsuccessful percutaneous coronary intervention

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Female, with DM	Percutaneous coronary intervention	-
Male, with DM	Percutaneous coronary intervention	-
Male, without DM	Percutaneous coronary intervention	-
Female, without DM	Percutaneous coronary intervention	-

Primary Outcome Measures

Name	Time	Method
MACE	8 years	All-cause death, non-fatal myocardial infarction, non-fatal stroke