Superficial Cervical Plexus Block for IJCL Pain Management

Not Applicable

Completed

• Conditions: Pain; Superficial Cervical Plexus Block
• Interventions: Procedure: Superficial Cervical Plexus Block; Procedure: Local Infiltrate

• Registration Number: NCT05252832
• Lead Sponsor: Cleveland Clinic Akron General

Brief Summary

This is a prospective randomized trial evaluating the effect of SCPB on reported patient pain following IJCL placement as compared to local infiltrate.

Detailed Description

The goal of this study is to determine if SCPBs provide more pain control than local infiltrate of anesthetic for internal jugular venous cannulation. The investigators hypothesis that patients who receive the SCPB will have a lower VAS rating on average than those who receive local infiltration following internal jugular venous cannulation. To test this, the investigators will be approaching eligible patients for inclusion in a research study. If the patients consent, the patients will be randomly assigned the standard of care treatment or the SCPB. The investigators will then ask the patients to rate pain following insertion of the central line. The investigators will also evaluate different aspects of the patient's hospital course to evaluate their outcomes.

Study Timeline

• Study First Submitted: 2021-12-07
• Study Start: 2022-01-15
• Study First Submitted QC: 2022-02-14
• Study First Posted: 2022-02-23
• Primary Completion: 2024-01-20
• Study Completion: 2024-12-31
• Status Verified: 2025-04
• Last Update Submitted: 2025-05-01
• Last Update Posted: 2025-05-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• Patients who are 18 years and older, and;
• Present to the Akron General Emergency Department (Main) between March 1, 2021 and December 1, 2022, and;
• Require IJVC as a part of their clinical care.

Exclusion Criteria

• Patients who are intubated; or
• Patients who undergo CPR; or
• Patients who have an allergy to lidocaine or bupivacaine; or
• Patients who have a contraindication to receiving a superficial cervical plexus block such as cellulitis over Erb's point or the internal jugular vein, abnormal anatomy, or prior surgery to the area.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
SCPB	Superficial Cervical Plexus Block	-
Local Infitrate	Local Infiltrate	-

Primary Outcome Measures

Name	Time	Method
Visual Analog Scale Rating	30 minutes post central line placement	The average Visual Analog Scale (VAS) rating in patients who receive the SCPB during internal jugular venous cannulation versus the average VAS in patients receiving local infiltration. The scale is from 0-10, with 0 meaning no pain and 10 meaning the most pain I have ever experienced.

Secondary Outcome Measures

Name	Time	Method
Complications	Duration of emergency department and inpatient encounter, typically no more than 7 days.	To determine if SCPBs are associated with higher complication rates than local infiltration with internal jugular venous cannulation. Complications will be defined as arterial injury, lacerations of the vena cava, mediastinal vessels, and right atrium, hematoma formation, retained guide wire, pulmonary complications including pneumothorax, pneumomediastinum, chylothorax, tracheal injury, injury to the recurrent laryngeal nerve, and air embolus, tracheal injury, arrhythmia, cardiac arrest, device dysfunction, device infection, and venous thrombosis.

Trial Locations

Locations (1)

Cleveland Clinic Akron General; 🇺🇸 Akron, Ohio, United States