Stent placement in Obstructive Colorectal Cancer Changing Blood and Tissue Biomarkers
Not Applicable
- Conditions
- Neoplasms
- Registration Number
- KCT0000835
- Lead Sponsor
- Gachon University Gil Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
1. Age > 20 years
2. Patients with malignant colorectal obstruction
3. Overt symptom and sign
4. Endoscopic stenting
5. Obtained informed concent and aggrement from patients after adequate explanation
Exclusion Criteria
1. Bleeding tendency
2. Uncontrolled systemic disease
3. Pregnant or lactating women
4. Age < 20 years
5. Patients who refuse or who is unable to give informed consent on tissue sampling for the study
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ischemia associated markers (such as HIF), epithelial-mesenchymal transition associated markers (such as E-cadherin, snail, twist, vimentin)
- Secondary Outcome Measures
Name Time Method Baseline characteristics (age, gender, tumor location, laboratory findings), complication, hospital stay, time of operation, etc