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Clinical Trials/NCT03376906
NCT03376906
Completed
N/A

The Effects of High Intensity Interval Exercise With 1- and 3- Min Recovery Times in Obese

Federal University of Paraíba0 sites12 target enrollmentJune 5, 2016

Overview

Phase
N/A
Intervention
Not specified
Conditions
Obesity
Sponsor
Federal University of Paraíba
Enrollment
12
Primary Endpoint
Forearm Blood Flow and Vascular Conductance
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

Obesity is a complex and multifactorial disease. Excess weight is related to endothelial dysfunction, inflammation and oxidative stress which increases the risk for cardiovascular diseases. High-intensity interval exercise can release vasodilatory substances and promote increased muscle blood flow.

Detailed Description

This study evaluated the effects of the recovery interval duration (1 vs. 3 min) in high intensity interval exercise (HIIE) on the hemodinamics responses in obese individuals. Twelve obese subjects (27 ± 3.8 yrs) were evaluated, who underwent three experimental sessions with a randomized crossover design: one control session (no exercise) and two HIIE sessions with the same workload (10 x 1min @92%VO2max / 1\[HIIE 1\] or 3\[HIIE 3\] min @0%). Forearm blood flow (FBF) and blood pressure (BP) were measured before and after the experimental sessions. Heart rate and relative perceived exertion were assessed during HIIE.

Registry
clinicaltrials.gov
Start Date
June 5, 2016
End Date
January 30, 2017
Last Updated
8 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Federal University of Paraíba
Responsible Party
Principal Investigator
Principal Investigator

Yokiny Silva

Physiotherapist

Federal University of Paraíba

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Forearm Blood Flow and Vascular Conductance

Time Frame: Up to 2 years

Forearm muscular blood flow was obtained through the venous occlusion plethysmography technique (19). For this, a silicon tube filled with mercury and connected to a low-pressure transducer was placed around the forearm, 5 cm away from the humeral-radial joint, connected to a plethysmograph (Hokanson® / EC6 plethysmograph, Bellevue, Washington, USA). A cuff was placed around the wrist and another at the upper arm, and the wrist cuff was inflated to a supra-systolic level every 1 min before measurements start. The arm cuff was inflated above the venous pressure at 10 s intervals for a period of 7 to 8 s. The increase in tension in the silastic tube reflects the increase in the volume of the forearm, which indicates vasodilation. The muscle flow wave signal was collected and stored on the WINDAQ DI 200 DATAQ program. Vascular conductance in the forearm was calculated by the blood flow ratio in the forearm (mL.min-1.100mL-1) and mean arterial pressure (mmHg) multiplied by 100.

Secondary Outcomes

  • Heart rate(Up to 2 years)
  • Blood pressure(Up to 2 years)

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