Establishment of ketogenic diet therapy guidance in Japanese patients with ADPKD - Ketogenic diet therapy in Japanese ADPKD

Department of Urology, Juntendo University Graduate School of Medicine0 个研究点目标入组 100 人开始时间: 2023年11月27日最近更新: 2024年1月22日

适应症

试验速览

暂无简介。

•(1) poorly controlled diabetes mellitus with HbA1C > 8.0 (2) Uncontrolled dyslipidemia with LDL cholesterol > 4 mmol/L or triglycerides > 3 mmol/L (3) Uncontrolled hypertension (SBP > 160 and/or BP > 100 mm Hg on 3 occasions) (5) Hyperkalemia (>5.5 mmol/l). (6) Significant disease such as malignancy within the past 5 years, autoimmune disease under immunosuppressive treatment (8) On any medication (SGLT2 inhibitor) or investigational drug that may affect the safety of the ketogenic diet (since bardoxolone methyl for ADPKD is under investigation in Japan). (12) Food sensitivities or allergies incompatible with the nutritional program (13) Subject is already compliant with a ketogenic diet or fasting (14) Current or past history of eating disorders or eating behaviors (16) Ulcerative colitis, irritable bowel syndrome, Crohn's disease, or gallbladder disease (17) BMI less than 18

发起方

Department of Urology, Juntendo University Graduate School of Medicine