Mifepristone in pre-induction cervical ripening in term pregnancy

Not Applicable

• Conditions: Health Condition 1: O80- Encounter for full-term uncomplicated delivery

• Registration Number: CTRI/2021/06/033951
• Lead Sponsor: Indian Navy

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Age between 18 and 40 years; singleton live pregnancies; cephalic presentation, unripe uterine cervix at the moment of enrollment (Bishop score less than 6), intact membranes, reactive FHR pattern in live fetus, no contraindication for vaginal delivery and no contraindication for labor induction with mifepristone or prostaglandin . (Bishop score will be calculated as recommended by Royal College of Obstetricians and Gynecologists)

Exclusion Criteria

Myoma / uterine anomaly, parity greater than 3, severe hyper- tension/preeclampsia, prior cesarean deliveries, impaired renal, adrenal, or hepatic function, fetal malformations, breech presentation, estimated fetal weight ( >4500 or <2500g), any concerns about the well-being of the fetus, any medical indication for scheduled cesarean delivery

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary aim is to evaluate the change in Bishop�s score with oral mifepristone in term pregnancy and to assess number of women going into spontaneous labor within 48 hours.Timepoint: Primary aim is to evaluate the change in Bishop�s score with oral mifepristone in term pregnancy and to assess number of women going into spontaneous labor within 48 hours.

Secondary Outcome Measures

Name	Time	Method
Secondary outcome is to assess the enrollment-induction to delivery interval; mode of delivery; and neonatal outcomes (NICU admission more than 24 hours).Timepoint: 48 hours