Comparison of intubation rate between high-flow nasal oxygen therapy and noninvasive ventilation in suspected sepsis patients with acute respiratory failure in ED: a retrospective cohort study
Recruiting
- Conditions
- To compare the intubation rate, 28-day mortality rate, hospital length of stay, and ventilator free day between high-flow nasal and noninvasive ventilation in patient suspected sepsis with respiratory failure in emergency department.High-flow nasal cannula, noninvasive ventilation, acute respiratory failure
- Registration Number
- TCTR20231109004
- Lead Sponsor
- /A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 544
Inclusion Criteria
Patients who visit Ramathibodi ED with suspected sepsis and acute respiratory failure defined by at least one of these: respiratory rate > 25, SpO2 <90, PaO2-to-FiO2 ratio <300 or clinical presentation of respiratory distress (such as accessory muscles use or abdominal paradox)
Exclusion Criteria
1. Patients needed for immediate intubation
2. Patients presented with cardiac arrest
3. Patients who referred from other department or hospital with high-flow nasal cannula or noninvasive ventilation
4. Patients with a do-not-intubate order
5. Patients on home positive airway pressure (PAP) therapy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intubation rate 48 hours odds ratio
- Secondary Outcome Measures
Name Time Method 28-day mortality rate 28 days odds ratio