A Survey of Nutritional Status of Patients After Hematopoietic Stem Cell Transplantation
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Change from Baseline food intake at 6 months
研究概览
简要总结
The main objectives of this study were :(1) to comprehensively and systematically evaluate the nutritional status of patients after hematopoietic stem cell transplantation. (2) to explore the effect of nutritional factors on the prognosis of patients treated by hematopoietic stem cell transplantation.
详细描述
This study is devised to investigate nutritional status in patients who have undergone hematopoietic stem cell transplantation in the First Affiliated Hospital of Soochow University. Evaluation time points include the day before receiving conditioning regimen, post-transplantation 180 days, the nutritional status of patients were systematically evaluated from the aspects of food intake, physical activity level, body composition, blood biochemistry, etc. Also, the effect of nutritional factors on prognosis of hematopoietic stem cell transplantaion patients will be evaluated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 15 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who undergo hematopoietic stem cell transplantation in the First Affiliated Hospital of Soochow University.
- •Having a life expectancy of more than 3 months
排除标准
- •Not willing to participate in the investigation
- •Age less than 15 years old or more than 80 years old
结局指标
主要结局
Change from Baseline food intake at 6 months
时间窗: 6 months
24-hour dietary record and semi-quantitative food frequency questionnaire are used to evaluate the eating condition of patients
Change from Baseline fat mass at 6 months
时间窗: 6 months
Body composition analyzer INBODY S10 (bioelectrical impedance method) is used to analyze the content of fat mass（ kilograms）
Change from Baseline fat free mass at 6 months
时间窗: 6 months
Body composition analyzer INBO DY S10 (bioelectrical impedance method) is used to analyze the content of fat free mass（ kilograms）
Change from Baseline albumin level in blood at 6 months
时间窗: 6 months
The content of albumin in blood is determined.
次要结局
- Overall survial(3 years)
- Event free survival(3 years)
研究者
Sheng-Li Xue, MD
Associate Professor
The First Affiliated Hospital of Soochow University