NL-OMON37785
Completed
Not Applicable
Search for Genetic Factors in Parkinson*s disease - Erasmus GPS (Erasmus Genetic Parkinson Study)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Parkinsonism
- Sponsor
- Erasmus MC, Universitair Medisch Centrum Rotterdam
- Enrollment
- 700
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- The probands (index cases) must have a diagnosis of idiopathic Parkinson\*s disease according to the established clinical criteria (familial or sporadic disease).
- •\- The relatives of the probands are first\-, second\-, or third\-degrees relatives of the probands; they might or might not have Parkinson\*s disease.
- •\- The unrelated controls, as well as their first degree relatives, must be free from clinical signs of Parkinson\*s disease and dementia.
- •\- All subjects (probands, relatives, controls) must be 18 years of age at recruitment.
- •\- All subjects (probands, relatives, controls) might be male or female.
- •\- All subjects (probands, relatives, controls) must have signed the informed consent (before entry into study). In case of a legally incapacited subject, for instance due to cognitive impairment, the legal representative will be approached to obtain informed consent.
Exclusion Criteria
- •\- Subjects who are unable to speak and be interviewed in Dutch or English (to ensure validity of the interviews).
- •\- Patients with secondary forms of parkinsonism (such as drug\-induced, toxic, vascular, tumour)
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Not Applicable
Search for Genetic Factors in Parkinson's Disease - IINL-OMON51549Erasmus MC, Universitair Medisch Centrum Rotterdam700
Not yet recruiting
Not Applicable
Genetic screening in Parkinson*s disease patients to identify GBA1 mutation carriers for future clinical trials.Parkinson's disease10028037NL-OMON56348Vanqua Bio Inc.1,000
Active, not recruiting
Not Applicable
Genetic screening for GBA1 in Parkinson’s disease patientsParkinson's disease, ParkinsonismNervous System DiseasesISRCTN99451262Vanqua Bio Inc.1,000
Completed
Not Applicable
Genetic screening in Parkinson*s Disease in order to identify patients who can participate in clinical trials with new targeted therapiesmovement disorderParkinson's disease10028037NL-OMON45734Centre for Human Drug Research1,000
Recruiting
Not Applicable
Study to investigate mutations in the GBA1 and LRRK2 genes in Parkinson’s Disease patients.Parkinson’s DiseaseNL-OMON23101CHDR1,000