NL-OMON51549尚未招募不适用
Search for Genetic Factors in Parkinson's Disease - II - GPS2 (The ErasmusMC Genetics of Parkinson Study - II)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 700
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 16 至 99（—）
入选标准
- •- The probands (index cases) must have a diagnosis of idiopathic Parkinson's
- •disease according to the established clinical criteria (familial or sporadic
- •- The relatives of the probands are first-, second-, or third-degrees relatives
- •of the probands; they might or might not have Parkinson's disease.
- •- Due to possible shared etio-pathogenetic pathways, relatives of PD probands
- •- The unrelated controls, as well as their first degree relatives, must be free
- •from clinical signs of Parkinson's disease and dementia.
- •-All subjects (probands, relatives, controls) must be 16 years of age at
- •recruitment.
- •-All subjects (probands, relatives, controls) might be male or female.
- •-All subjects (probands, relatives, controls) must have signed the informed
- •consent (before entry into study). In case of a legally incapacitated subject,
- •for instance due to cognitive impairment, the legal representative will be
- •approached to obtain informed consent.
排除标准
- •- Subjects who are unable to speak and be interviewed in Dutch or English (to
- •ensure validity of the interviews).
- •- Patients with secondary forms of parkinsonism (such as drug-induced, toxic,
- •vascular, tumor)
研究者
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