Comparison of total intravenous anesthesia with propofol versus desflurane as inhalational agent on surgical field quality in functional endoscopic sinus surgery: A randomized, prospective, comparative, observational study
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- surgical field quality
研究概览
简要总结
This study aims to compare the surgical field quality and emergence from anaesthesia in two groups of patients, one group receiving PROPOFOL and the other group receiving DESFLURANE. Both the groups will be receiving DEXMEDETOMIDINE infusion.
Bispectral Index monitoring will be done to standardise the depth of anaesthesia in both groups.
To achieve bloodless surgical field during endoscopic sinus surgery, hypotensive anaesthesia plays a very crucial role. Controlled hypotension, defined as MAP of 55-65 mm Hg, , helps to control blood loss during surgery and improve the quality of surgical field by using anaesthetic and vasoactive agents. Total Intravenous Anaesthesia (TIVA) with propofol has long been used in endoscopic sinus surgeries to decrease intraoperative blood loss and reduce duration of surgery. The use of Dexmedetomidine has also been tried to achieve hypotensive anaesthesia in Functional Endoscopic Sinus Surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Age- 18 to 65 years of both gender ASA grade I and II undergoing Functional Endoscopic Sinus Surgery.
排除标准
- •Age <18 and >65 years ASA grade III and IV.
结局指标
主要结局
surgical field quality
时间窗: at 5 minutes, at 10 minutes, 20 minutes, at 30 minutes, at 40 minutes
次要结局
- 1.Time of emergence from anaesthesia(2.Requirement of rescue hypotensive agent)