ChiCTR2400084947尚未招募Unknown
Computer Use for Seniors on Mood Improvement and Logic Enhancement (CU-SMILE)
Knowledge Transfer Project Fund (KPF) of the Chinese University of Hong Kong, and Social Innovation and Entrepreneurship Development Fund (SIE Fund) of the Government of HKSAR1 个研究点 分布在 1 个国家开始时间: 2024年6月1日最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 试验地点
- 1
- 主要终点
- Mood symptoms
研究概览
简要总结
To improve mood symptoms in community-living older adults with depression using computerized cognitive training
研究设计
- 研究类型
- Interventional
- 主要目的
- 单臂
入排标准
- 年龄范围
- 60 至 100（—）
- 性别
- All
入选标准
- •are community-living Chinese individuals aged 60 years and older, and having a primary diagnosis of major depressive disorder (single or recurrent episodes without psychotic features) based on the DSM-5 criteria, with cognitive symptoms [Item 8 (slowness of thought and speech, impaired ability to concentrate) score ≥2 in HAM-D], but without dementia (based on the age- and education-specific cutoff of HK-MoCA).
排除标准
- •Individuals who have suicidal idea, psychotic symptom, or are treatment-resistant [history of electroconvulsive therapy, transcranial magnetic stimulation, or no clinical response to ≥2 different classes of antidepressants] will be excluded and referred to the psychiatric services of the Hospital Authority. Other exclusion criteria are non-Chinese; living in care homes; having history or ongoing substance abuse (including alcohol), mania, bipolar or psychotic disorder, posttraumatic stress disorder, anxiety disorder, personality disorder, or mental disorder due to organic cause; having history of traumatic brain injury, Parkinson’s disease, stroke, dementia, or scoring below HK-MoCA cutoff; or having language barrier or impairment in communication (poor vision or hearing despite correction).
研究组 & 干预措施
Depression group
结局指标
主要结局
Mood symptoms
次要结局
未报告次要终点
研究者
研究点 (1)
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