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临床试验/NCT00786617
NCT00786617已完成不适用

The Efficacy of Nurse-driven, Protocol Guided Ventilator Weaning in a Medical-Surgical ICU

St. Luke's-Roosevelt Hospital Center0 个研究点目标入组 202 人开始时间: 2007年12月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
202
主要终点
Average Length of Stay on Ventilator

研究概览

简要总结

  1. Mechanically ventilated patients weaned by nurse-driven ventilator weaning protocol will have a mean length of stay on ventilator at least one day shorter than patients weaned by physician-initiated, non-protocol methods
  2. Mechanically ventilated patients weaned by nurse-driven ventilator weaning protocol will have al least similar Ventilator, ICU, and Hospital Length Of Stay (LOS) compared to patients weaned by physician-initiated, non-protocol method
  3. Nurse-driven ventilator weaning protocol is well accepted by other services: physicians, nurses, and respiratory therapists.

详细描述

Ventilatory support is one of the most common indications for admission to ICU (1).

The duration of mechanical ventilation is associated with several serious complications, increase mortality, prolong ICU stay, and increase hospital cost (7,8).

Traditionally, the process of ventilator weaning is initiated and carried out my physicians.

Recently, there have been few studies that supported the utility of protocol guided weaning algorithms. Its use have been associated with earlier initiation of weaning, leading to shorter ventilator time, and a trend for shorter ICU length-of-stay and lower hospital costs (1,2,4,9) Several studies have also shown the relative safety of utilizing nursing (3) and RT staff alone or in cooperation with medical staff in the weaning of patients from mechanical ventilation (1,2,6).

We recently developed a nurse-driven ventilator weaning protocol for all ICUs at St. Luke's and Roosevelt hospitals. The protocol was approved by the Critical Care Committee and is implemented as of May 2007. All ICU nurses, respiratory therapists, and ICU physicians have been educated on this protocol We plan to prospectively collect data to look at length of stay on mechanical ventilation in patients weaned by nurse-driven ventilator weaning protocol. We plan to compare such data to retrospectively collected ventilator LOS data in patients weaned by physician-initiated ventilator weaning method.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Receiving MV for at least 24 hours in the ICU
  • Meeting established protocol criteria for a vent wean trial

排除标准

  • Patients in whom MV was actively withdrawn for terminal wean
  • Brain dead patients on MV
  • Age <18 years old
  • Transfers from other hospitals or health care facility who were ventilator dependent

结局指标

主要结局

Average Length of Stay on Ventilator

时间窗: up to 5 months

次要结局

  • Level of acceptance of nurse-driven vent weaning protocol(up to 5 months)
  • Treatment intensity and resource allocation: Cost of ICU care per year(up to 5 months)
  • ICU mortality(up to 5 months)
  • Hospital mortality(up to 5 months)

研究者

申办方类型
Other
责任方
Sponsor

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