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临床试验/NCT06157593
NCT06157593尚未招募不适用

Neurally Adjusted Ventilatory Assist for Weaning From Invasive Mechanical Ventilation in Critically Ill Children: A Randomised Control Trial

Chulalongkorn University2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年2月最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
60
试验地点
2
主要终点
PICU length of stay

研究概览

简要总结

The goal of this clinical trial is to compare weaning from mechanical ventilation in critically ill children. The main questions it aims to answer are:

  • Will weaning with neurally adjusted ventilatory assist (NAVA) mode ventilation result in shorter ventilator day than synchronised intermittent mandatory ventilation (SIMV) mode?
  • Will weaning with NAVA mode ventilation result in shorter paediatric intensive care unit (PICU) length of stay than SIMV mode? Participants will be randomised to NAVA or SIMV group for weaning from mechanical ventilation, then PICU outcomes from both groups will be collected, analysed and compared.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
1 Month 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • all critically ill children admitted to PICU

排除标准

  • failure to obtain informed consent

结局指标

主要结局

PICU length of stay

时间窗: immediately after PICU discharge

number of days patients remain in PICU

ventilator day

时间窗: immediately after extubation

number of days patients receive mechanical ventilation

次要结局

  • asynchrony index(20-minute period randomly captured from the day of extubation)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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