Elucidating the Relationship Between Ultra-Processed Food Consumption, Executive Function, and Hunger-Related Hormones

Oklahoma State University1 个研究点分布在 1 个国家目标入组 20 人2024年1月1日

适应症Diet Habit

干预措施Education

概览

阶段: 不适用
干预措施: Education
疾病 / 适应症: Diet Habit
发起方: Oklahoma State University
入组人数: 20
试验地点: 1
主要终点: Plasma ghrelin
状态: 已完成
最后更新: 2个月前

概览研究者入排标准研究组 & 干预措施结局指标研究点相似试验

概览

简要总结

The purpose of this study is to examine potential effects of a diet characterized by UPF on hunger-related hormones and executive function. It entails a two-arm, crossover, randomized controlled trial.

注册库

clinicaltrials.gov

开始日期

2024年1月1日

结束日期

2024年10月1日

最后更新

2个月前

研究类型

Interventional

研究设计

Crossover

性别

All

研究者

发起方

Oklahoma State University

责任方

Sponsor

主要研究者

ABraun

Assistant Professor

Oklahoma State University

入排标准

入选标准

•Adults aged 18-55
•Willing to consume an entirely ultra-processed and entirely unprocessed diet for 3 days each (6 days in total)

排除标准

•Chronic disease that interferes with study-related activities
•Special diet that limits adherence to the intervention diets
•Visual impairment not corrected by glasses/contacts
•Pregnant or lactating

研究组 & 干预措施

Ultra-processed foods

Participants are instructed to consume only ultra-processed foods for 3 days.

干预措施: Education

Unprocessed foods

Participants are instructed to consume only unprocessed foods for 3 days.

干预措施: Education

结局指标

主要结局

Plasma ghrelin

时间窗: Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days)

Measured in picograms per milliliter (pg/mL)

次要结局

Plasma gastric inhibitory polypeptide (GIP)(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Plasma active amylin(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Plasma C-peptide(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Plasma active glucagon-like peptide-1 (GLP-1)(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Plasma glucagon(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Plasma insulin(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Plasma leptin(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Plasma monocyte chemoattractant protein-1 (MCP-1)(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Plasma pancreatic polypeptide (PP)(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Plasma peptide YY (PYY)(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Plasma secretin(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Body mass(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Body mass index(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Percent fat mass(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Body fat mass(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Percent lean mass(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Lean mass(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Food addiction according to the Yale Food Addiction Scale Version 2.0(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Behavioral Inhibition System/Behavioral Approach System Scale(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Executive Function: Tower Test (Delis-Kaplan Executive Function System)(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Executive Function: Color-Word Interference Test (Delis-Kaplan Executive Function System)(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))
Ultra-processed food intake(Measured at three times: baseline, post-first diet arm (3 days), post-second diet arm (6 days))