Ultra Processed Foods Consumption and Impact in Rheumatic Diseases.

Recruiting

• Conditions: Rheumatoid Arthritis; Spondyloarthritis; Osteoarthritis

• Registration Number: NCT06776965
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Ultra-processed foods (UPF) represent one of the mainstays of today's diet. They are defined by the NOVA classification system. It was demonstrated that UPF consumption was associated with activity of inflammatory bowel diseases with underlying mechanisms not fully identified yet. It is suspected that UPF constituents could modify the gut microbiota, increase intestinal barrier permeability and directly engage immune surveillance systems, effects that could individually or synergistically increase the risk of immunomediated diseases. As some pathophysiological mechanisms are shared among IBD and rheumatic diseases, we have wondered if UPF consumption could be associated with increased risk of rheumatic disease and/or with their activity.

Our primary aim will be to study the pattern of UPF consumption in patients with rheumatic diseases. Our secondary objectives will be to study the activity of diseases according to UPF consumption.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-01-10
• Study First Submitted QC: 2025-01-10
• Study First Posted: 2025-01-15
• Study Start: 2025-03-31
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-10
• Last Update Posted: 2025-04-11
• Primary Completion: 2026-03-31
• Study Completion: 2026-11-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 240

Inclusion Criteria

• Age > 18 years
• chronic rheumatic disease (Rheumatoid arthritis, spondyloarthritis, osteoarthritis)
• ability to perform questionnaires

Exclusion Criteria

• Judicial protection measure
• Refusal to participate in the study
• Suffering from 2 rheumatic disease simultaneously

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Describe the consumption of ultra-processed foods in patients with chronic inflammatory rheumatism	At baseline	Describes the consumption of ultra-processed foods in patients with chronic inflammatory rheumatism using a self-assessment questionnaire (Score UPF Nova Screener) completed at baseline, 6 and 12 months.

Trial Locations

Locations (1)

Edouard Herriot Hospital; 🇫🇷 Lyon, France