Phase 1 study of neoadjuvant chemotherapy with capecitabine/bevacizumab for locally advanced lower rectal cancer.
Phase 1
- Conditions
- lower rectal cancer
- Registration Number
- JPRN-UMIN000005289
- Lead Sponsor
- Osaka City University Graduate School of Mediceine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 6
Inclusion Criteria
Not provided
Exclusion Criteria
1)distant organ metastasis 2)previous chemotherapy for colorectal cancer 3)previous radiotherapy for the pelvis 4)history of another malignancy witjin the last 5years
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method MTD, RD
- Secondary Outcome Measures
Name Time Method pCR rate, response rate, R0 resection rate