Effect of N-acetylcysteine supplementation in treatment of methadone maintenance treatment patients
Phase 3
- Conditions
- Addiction.Other psychoactive substance related disorders
- Registration Number
- IRCT20170420033551N10
- Lead Sponsor
- Kashan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Patients under methadone maintenance treatment
Age of 18 to 50 years old
Evaluated by the drug abuse section of the Structured Clinical Interview for DSM-IV
Exclusion Criteria
Unwillingness to cooperate
Consumption of antioxidant, and anti-inflammatory supplements during the last 3 months
High blood pressure
Hypothyroidism or hyperthyroidism
Pregnant women
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Depression. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Beck Depression Inventory (BDI).;Anxiety. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Beck Anxiety Inventory (BAI).;Sleep quality. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Pittsburgh Sleep Quality Index (PSQI).
- Secondary Outcome Measures
Name Time Method