Effects of Whey Protein Intervention on Body Composition and Muscle Function in the Elderly With Sacropenia

Not Applicable

• Conditions: Healthy
• Interventions: Dietary Supplement: protein supplement

• Registration Number: NCT02490410
• Lead Sponsor: Huilian Zhu

Brief Summary

The purpose of this study is to compare the effects of different dose of whey protein intervention(in a daily dose of 0g, 10g, 20g) on lean body mass,body fat composition and muscular function state in the elderly with sacropenia.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2015-06-30
• Status Verified: 2015-07
• Study Start: 2015-07
• Study First Submitted QC: 2015-07-02
• Last Update Submitted: 2015-07-02
• Study First Posted: 2015-07-03
• Last Update Posted: 2015-07-03
• Primary Completion: 2016-04
• Study Completion: 2016-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• People aged over 65 years.
• Usual gait speed less than 0.8m/s.
• Willing to participate in the study, consume the test product and perform all measurements.

Exclusion Criteria

• nervous system disease.
• Other diseases with movement disorder such as stroke,fracture,arthritis.
• people who unconsciousness and can not complete questionnaire
• long-term regular use of protein and antioxidant.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
whey protein+soy protein	protein supplement	10g whey protein + 10g soy protein per day orally for 6 months
whey protein	protein supplement	2 x 10g whey protein per day orally for 6 months
soy protein	protein supplement	2 x 10g soy protein per day orally for 6 months

Primary Outcome Measures

Name	Time	Method
lean body mass	up to 6 months	At baseline, 3 and 6 months, investigators will use DXA to examine lean body mass and body fat composition
muscular function state	up to 6 months	At baseline, 3 and 6 months, investigators will use the Short Physical Performance Battery (SPPB) to test muscular function state

Secondary Outcome Measures

Name	Time	Method
plasma amino acid spectrum, especially branched chain amino acid spectrum	up to 6 months	At baseline and 6 months, blood samples will be drawn and plasma amino acid spectrum, especially branched chain amino acid spectrum will be tested