The Effect of Whole Blood Viscosity on Contrast-Induced Nephropathy Development in Patients Undergoing Percutaneous Coronary Intervention
- Conditions
- Percutaneous Coronary Intervention Patients
- Registration Number
- NCT04703049
- Lead Sponsor
- Bursa Postgraduate Hospital
- Brief Summary
In our study, we aimed to investigate how whole blood viscosity (WBV) affects the development of contrast-induced nephropathy (CIN) in patients undergoing percutaneous coronary intervention (PCI).
- Detailed Description
In our study, 500 patients who applied to the cardiology clinic and underwent PCI for elective procedure, ST segment elevation myocardial infarction (STEMI), and non-STEMI were prospectively included. Before the procedure, we calculated WBV using the formula \[(0.12 × hematocrit) + (0.17 × (total protein - 2.07)\]. We defined CIN as the absolute (≥0.5 mg/dl) or relative increase (≥25%) in serum creatinine 48-72 h after exposure to a contrast agent compared with baseline serum creatinine values.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 500
- patients between ages 18 and 90
- underwent PCI in our hospital between
- Patients with chronic kidney disease (CKD) who underwent hemodialysis or peritoneal dialysis
- Patients who underwent to coronary bypass surgery within 48 h were excluded from the study.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Contrast Induced Nephropathy 48 to 72 hours CIN was defined as an increase in serum creatinine levels greater than 0.5 mg/dl or 25% or more increase compared to basal serum creatinine levels 48 to 72 h after exposure.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Bursa Yüksek İhtisas Hastanesi
🇹🇷Bursa, None Selected, Turkey