Documentation of the Efficacy of Desmopressin Within the Context of Surgical Procedures
- Registration Number
- NCT02368730
- Lead Sponsor
- Ferring Pharmaceuticals
- Brief Summary
In this non-interventional multicentre, prospective, observational cohort study, the efficacy of desmopressin is evaluated in patients with platelet dysfunction due to acetylsalicylic acid or cox-1-inhibitors within the context of surgical procedures.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 23
Inclusion Criteria
- Pre-, peri- or postoperative treatment with a standard dose of desmopressin as a result of platelet dysfunction (disturbance of blood platelet function) due to treatment with acetylsalicylic acid or cox-1-inhibitor.
- Decision on the therapy with MINIRIN parenteral 4 Microgram/ml solution for injection has already been made independently by the physician beforehand
- The patients (≥ 18 years) have been informed about the non-interventional study and have given their written consent for participation
Exclusion Criteria
- Participation in a clinical trial
- Treatment with acetylsalicylic acid for cardiovascular indications
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description desmopressin desmopressin Treatment according to standard clinical practice.
- Primary Outcome Measures
Name Time Method Change in platelet function pre- and post-administration of desmopressin From baseline up to 7 days As measured by Platelet Function Analyzer (PFA) 100/200
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Charité - Universitätsmedizin Berlin (there may be other sites in this country)
🇩🇪Berlin, Germany