Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients

Phase 4

• Conditions: Headache; Epilepsy; Dizziness

• Registration Number: NCT00132223
• Lead Sponsor: University Hospital Muenster

Brief Summary

Angiographies of the supra-aortic vessels by magnetic imaging have become common recently. So it was the purpose of this study to evaluate the imaging potential of different contrast agents.

Three contrast agents for magnetic resonance imaging are compared in angiographies of the supra-aortic arteries in a intraindividual study of 10 patients.

All applications of these contrast agents are performed with a flow of 2 ml/s. One contrast medium is applicated a second time with a reduced flow of 1 ml/s.

The angiographies of the supra-aortic vessels are evaluated by two experienced readers in a consensus reading. The signal/noise- and contrast/noise-ratio of anatomic vessel segments of the carotic and vertebral arteries are measured and compared to each other.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-04
• Study First Submitted: 2005-08-18
• Study First Submitted QC: 2005-08-18
• Study First Posted: 2005-08-19
• Study Completion: 2005-12
• Status Verified: 2006-04
• Last Update Submitted: 2006-04-11
• Last Update Posted: 2006-04-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Headache
• Epilepsia
• Dizziness

Exclusion Criteria

• Pregnancy
• Metal implants (e.g. pacemaker)
• Contraindication for contrast agent
• Multiple allergies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
intensity of vessels, muscle, air

Secondary Outcome Measures

Name	Time	Method
signal/noise ratio
contrast/nose ratio

Trial Locations

Locations (1)

University of Muenster, Dept. of Clinical Radiology; 🇩🇪 Muenster, Germany