PROUD Study - Preventing Opioid Use Disorders
Overview
- Phase
- Phase 4
- Intervention
- Guided mindfulness exercises
- Conditions
- Anesthesia
- Sponsor
- Emory University
- Enrollment
- 57
- Locations
- 1
- Primary Endpoint
- Total Post-operative Opioid Requirements With Non-opioid Drug Regimen
- Status
- Terminated
- Last Updated
- 2 years ago
Overview
Brief Summary
The objective of this study is to pilot an opioid free anesthetic protocol for patients undergoing total hip replacement.
Detailed Description
The objective of this study is to pilot an opioid free anesthetic protocol for patients undergoing total hip replacement. The study team identified alternative pharmacologic methods to block pain pathways to reduce or even eliminate the need for opioids in the intra- and postoperative periods, with the goal of decreasing or eliminating exposure to opioids. A secondary objective is to assess two core competencies for interprofessional collaborative practice (Interprofessional Communication and Teams; and Teamwork) within the interprofessional care team implementing the opioid free protocol.
Investigators
Kelly Wiltse Nicely
Assistant Professor
Emory University
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •Participants that do not speak English will not be eligible for participation in the study.
- •Individuals less than 18 years of age will not be included for participation in the study.
- •Individuals with cognitive impairment or the inability to provide informed consent will not be included in the study.
Arms & Interventions
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Guided mindfulness exercises
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Self-administered aromatherapy
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Baby aspirin
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Tylenol/Acetaminophen
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Pregabalin
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Prednisone
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Meloxicam
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Prilosec
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Tramadol
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Voltaren
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Zofran
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Pepcid
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Reglan
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Versed
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Lidocaine
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Propofol
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Ancef
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Tranexamic Acid (TXA)
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Decadron
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Bupivacaine hydrochloride
Prospective cases undergoing non-opioid drug regimen
Prospective study participants undergoing unilateral total hip replacement surgery and non-opioid drug regimen perioperatively
Intervention: Toradol
Outcomes
Primary Outcomes
Total Post-operative Opioid Requirements With Non-opioid Drug Regimen
Time Frame: Up to 5 weeks
Total post-operative opioid requirements (opioid dose) were calculated for participants receiving the non-opioid drug regimen, among participants who required post-operative opioid medication.
Secondary Outcomes
- Nebraska Interprofessional Education Attitude Scale (NIPEAS) Score for Professional Staff Arm(Prior to protocol implementation (baseline), halfway through the recruitment period (2 months) and after the last participant has been discharged from the hospital (4 months))