Evaluation of Human Efficacy of SOD Like Super Drink
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- TCI Co., Ltd.
- Enrollment
- 50
- Locations
- 2
- Primary Endpoint
- the change of Glutathione (GSH) of blood
Study Overview
Brief Summary
To assess the efficacy of SOD like Super Drink on anti-oxidant capacity, immuno regulation and skin for human
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Other
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 30 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •healthy adults aged between 30-65 years old
Exclusion Criteria
- •Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder
- •Patients with diseases of the skin, liver, kidney.
- •Female who is pregnant or nursing or planning to become pregnant during the course of the study.
- •Received facial laser therapy, chemical peeling or UV overexposure (> 3 hr/week) in the past 4 weeks.
- •Students who are currently taking courses taught by the principal investigator of this trial.
Arms & Interventions
placebo drink
Intervention: placebo drink (Dietary Supplement)
SOD like Super Drink
Intervention: SOD like Super Drink (Dietary Supplement)
Outcomes
Primary Outcomes
the change of Glutathione (GSH) of blood
Time Frame: Change from Baseline GSH at 8 weeks
venous blood was sampled to measure GSH
the change of Superoxide Dismutase (SOD) of blood
Time Frame: Change from Baseline SOD at 8 weeks
venous blood was sampled to measure SOD
the roughness of skin texture
Time Frame: Rating skin roughness from Baseline skin texture at 8 weeks
IRV full-face skin analyzer was utilized to measure skin texture. Units: arbitrary units
the change of skin elasticity
Time Frame: Change from Baseline skin elasticity at 8 weeks
Cutometer® was utilized to measure skin elasticity. Units: arbitrary units
the change of Total Anti-oxidative Capacity (TAC) of blood
Time Frame: Change from Baseline TAC at 8 weeks
venous blood was sampled to measure TAC
the change of Glutathione S-transferase (GST) of blood
Time Frame: Change from Baseline GST at 8 weeks
venous blood was sampled to measure GST
the volume of skin wrinkles
Time Frame: Volume change from Baseline skin wrinkles at 8 weeks
IRV full-face skin analyzer was utilized to measure skin wrinkles. Units: arbitrary units
the change of Malondialdehyde (MDA) of blood
Time Frame: Change from Baseline MDA at 8 weeks
venous blood was sampled to measure MDA
the change of immune-related cytokines of blood
Time Frame: Change from Baseline immune-related cytokines at 8 weeks
venous blood was sampled to measure immune-related cytokines
Secondary Outcomes
- the change of skin Transepidermal Water Loss (TEWL)(Change from Baseline TEWL at 8 week)
- the change of skin surface hydration(Change from Baseline skin surface hydration at 8 week)
- the change of Skin Erythema Index(Change from Baseline skin Erythema Index at 8 week)
- the change of Skin Melanin Index(Change from Baseline skin Melanin Index at 8 week)