NL-OMON47690已完成不适用
on-invasive assessment of lung remodelling in patients with pulmonary arterial hypertension (PAH) using [18F]-FLT PET imaging. - Imaging the primary disease process in PAH
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
研究概览
简要总结
Trial ended prematurely
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 64(—)
入选标准
- •In order to be eligible to participate in this study, a subject must meet all of the following criteria:
- •1.Diagnosis of PAH, according to ESC/ERS guidelines (ref: Galie ERJ 2015)
- •Unaffected BMPR2 mutation carrier
- •Normal control subjects
- •2. Age >50 and <80 years
排除标准
- •- Pregnant subjects
- •- Claustrophobia
- •- Inability to provide informed consent
- •- In case of PAH patients: TLC < 70%pred or radiographic evidence of interstitial lung disease
- •- In case of BMPR2 mutation carriers and normal control subjects, one or more of the following: abnormal spirometry, TLC < 70%, echocardiographic evidence of pulmonary hypertension
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