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Clinical Trials/NL-OMON47690
NL-OMON47690
Completed
Not Applicable

on-invasive assessment of lung remodelling in patients with pulmonary arterial hypertension (PAH) using [18F]-FLT PET imaging. - Imaging the primary disease process in PAH

Vrije Universiteit0 sites36 target enrollmentTBD
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Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
Vrije Universiteit
Enrollment
36
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

Trial ended prematurely

Registry
who.int
Start Date
TBD
End Date
January 9, 2020
Last Updated
2 years ago
Study Type
Observational invasive

Investigators

Eligibility Criteria

Inclusion Criteria

  • •In order to be eligible to participate in this study, a subject must meet all of the following criteria:
  • •1\.Diagnosis of PAH, according to ESC/ERS guidelines (ref: Galie ERJ 2015\)
  • •Unaffected BMPR2 mutation carrier
  • •Normal control subjects
  • •2\. Age \>50 and \<80 years

Exclusion Criteria

  • •\- Pregnant subjects
  • •\- Claustrophobia
  • •\- Inability to provide informed consent
  • •\- In case of PAH patients: TLC \< 70%pred or radiographic evidence of interstitial lung disease
  • •\- In case of BMPR2 mutation carriers and normal control subjects, one or more of the following: abnormal spirometry, TLC \< 70%, echocardiographic evidence of pulmonary hypertension

Outcomes

Primary Outcomes

Not specified

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