NL-OMON44254
Recruiting
Not Applicable
on-invasive assessment of lung remodeling in patients with idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH) using [11C]-Nintedanib or [18F]-FLT PET imaging. - Imaging the primary disease process in IPF and PAH
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Vrije Universiteit
- Enrollment
- 90
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •In order to be eligible to participate in this study, a subject must meet all of the following criteria:
- •1\. Diagnosis of IPF, according to ATS/ERS guidelines (ref Raghu AJRCCM 2011\)
- •Diagnosis of PAH, according to ESC/ERS guidelines (ref: Galie ERJ 2015\)
- •Unaffected BMPR2 mutation carrier
- •Normal control subjects
- •2\. Age \>18 and \<80 years
Exclusion Criteria
- •\- Claustrophobia
- •\- Inability to provide informed consent
- •\- In case of IPF patients: pulmonary hypertension suspected by echocardiography or proven by right heart
- •catheterization
- •\- In case of PAH patients: TLC \< 70%pred or radiographic evidence of interstitial lung disease
- •\- In case of BMPR2 mutation carriers and normal control subjects, one or more of the following: abnormal
- •spirometry, TLC \< 70%, echocardiographic evidence of pulmonary hypertension
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Phase 3
A study to find out the effectiveness of Homoeopathic medicines in Allergic asthma patientsCTRI/2022/10/046524Dr GEETHU K P
Completed
Not Applicable
on-invasive assessment of lung remodelling in patients with pulmonary arterial hypertension (PAH) using [18F]-FLT PET imaging.NL-OMON47690Vrije Universiteit36
Completed
Not Applicable
Study of the way unevenness in lung function changes with treatment in airways diseaseISRCTN12223638niversity of Oxford91
Completed
Not Applicable
Quantification of pulmonary vascular remodelling in pulmonary arterial hypertension patients using positron emission tomographyhigh blood pressure in the pulmonary circulationPulmonary arterial hypertension10037454NL-OMON41823Vrije Universiteit Medisch Centrum8
Not yet recruiting
Not Applicable
Role of lung ultrasound in assessment of Interstitial Lung DiseasesHealth Condition 1: J841- Other interstitial pulmonary diseases with fibrosisCTRI/2020/04/024820Maulana Azad Medical College