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EnSite NavX-Guided Coronary Sinus Mapping During CRT Implant

Not Applicable
Completed
Conditions
Congestive Heart Failure
Registration Number
NCT01615835
Lead Sponsor
Abbott Medical Devices
Brief Summary

Use of the EnSite NavX system to map the coronary vasculature during CRT implant

Detailed Description

Objective(s):

To determine the feasibility of CS mapping with NavX during Biventricular Implantable Cardioverter Defibrillator (BiV ICD) implantation.

Inclusion Criteria:

* Subject is between the age of 18 and 75 years

* Subject is willing and able to sign a study specific informed consent

* Subject is able to fulfill study requirements

* Meet the conventional criteria for implant of a BiV ICD, including; LVEF of ≤35%, QRS ≥ 120 ms and NYHA III-IV

* Have persistent CHF symptoms despite contemporary CHF medical therapy

* Stable and optimal medical therapy (stability is no changes in past 3 months).

* Documented history of ischemic or non-ischemic cardiomyopathy.

Exclusion Criteria:

* Have any standard device exclusions including tricuspid valve prosthesis/ replacement.

* Have a positive urine or serum pregnancy test (if female and of childbearing potential)

* Be currently participating in an IDE or IND study.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
16
Inclusion Criteria
  • Meet criteria for CRT implant including EF<35%, QRS>120ms, NYHA class III or IV
  • Persistent CHF symptoms despite optimization
  • Stable/optimal medical therapy
  • History of ischemic or non-ischemic cardiomyopathy
Exclusion Criteria
  • Any standard device exclusion including TVR
  • Positive pregnancy test
  • Currently participating in IDE/IND study

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Determine feasibility of CS mapping with EnSite NavX during CRT implantProcedural
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

Duke Medical Center

🇺🇸

Durham, North Carolina, United States

Medical College of Georgia

🇺🇸

Augusta, Georgia, United States

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