The efficacy of blood transfusions to improve microcirculatory oxygen delivery in anemic patients.

• Conditions: bloed doorstroming in de microcirculatie; acute myeloid leukemia. leukemia; 10038158; 10018865

• Registration Number: NL-OMON30782
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 75

Inclusion Criteria

1. Anemic patients and patients who under chemotherapy treatment receiving blood transfusion
2. Approval from the physician that will be treating the patients
3. Informed consent from each participating patient
4. Patients older than 18 years
5. Transfusion of blood from different storage age (more than 1 week difference in the duration of storage)
6. Transfusion of blood from storage age less than 1 week and more than 4 weeks.

Exclusion Criteria

1. Patients that did not sign an informed consent
2. Patients younger than 18 years

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Noninvasive measurements:<br /><br>Sidestream Dark-Field (SDF) Imaging-microcirculation quantification<br /><br>Fibre spectrophotometry and laser Doppler flowmetry (O2C)<br /><br><br /><br>Invasive measurements:<br /><br>Blood sample</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>N.v.t.</p><br>