The effects of red blood cell transfusion on the microcirculation in chronic anemic preterm neonates.

Recruiting

• Conditions: Microcirculation; smallest bloodvessels; 10038158; 10047066

• Registration Number: NL-OMON40949
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 24

Inclusion Criteria

- Gestational age below 32 weeks
- Chronic anemia determined by protocol *anemia in preterm infants* of the NICU department
Erasmus MC - Sophia
- Written informed consent

Exclusion Criteria

- Any known congenital or chromosomal defects will be excluded from this study.
- Acute bleeding (i.e. pulmonary bleeding, gastrointestinal bleeding)
- Any known hematological disorder (i.e. pathological hemolysis)
- Absence of written informed consent

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Vessel density and microvascular flow index derived from CytoCam imaging.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Flow, venous saturation and hemoglobin concentration measured by O2C.</p><br>