Effects of Red Blood Cell Transfusions on Distant Metastases ofOral Squamous Cell Carcinomas

• Conditions: C14: Malignant neoplasm of other and vaguely defined localisations of the lip, oral cavity and pharynx; C00-C14; Malignant neoplasms of lip, oral cavity and pharynx

• Registration Number: DRKS00031677
• Lead Sponsor: niversitätsklinikum Freiburg, Klinik für Mund-, Kiefer-, Gesichtsschirurgie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-12-20
• Results First Posted: 2021-12-28
• Study Start: 2023-05-02
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 580

Inclusion Criteria

Primary operated squamous cell carcinoma of the oral cavity, period of initial diagnosis 1.1.2000 - 31.12.2019.

Exclusion Criteria

Other tumour entities, second cancers, patients primarily irradiated or treated with chemotherapy, R1 status, no complete patient file, no regular participation in the follow-up programme (at least 12 months).

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rate of distant metastasis after tumour surgery in relation to allogeneic blood transfusions compared to other independent variables

Secondary Outcome Measures

Name	Time	Method
Changes in overall survival and progression-free survival in relation to allogeneic blood transfusions compared to other independent variables.